What is the clinical evidence from this study?

Study design: Other. Population: Developmental pattern of slow myosin expression. Intervention: Developmental stage (embryonic vs fetal myoblasts). Primary outcome: Expression of slow and embryonic (fast) myosin.

December 1, 1988The Journal of Cell Biology

The expression of slow myosin during mammalian somitogenesis and limb bud differentiation.

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Key result

Embryonic myoblasts in mammals coexpress slow and embryonic (fast) myosin, whereas fetal myoblasts express only embryonic (fast) myosin.

Authors

EVE. VivarelliSapienza University of Rome WBWendy E. BrownHospital for Special Surgery RWRobert G. WhalenMaxygen (United States)

Discussion

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Implication

Distinguishes embryonic from fetal myoblast lineages; leaves open relevance to muscle regeneration or congenital disorders.

PICO

Population

Mouse embryos and cultured myogenic cells from the somitic stage to the period of secondary fiber formation.

Exposure / Comparator

Developmental stage (embryonic vs fetal myoblasts)

Primary Outcome

Expression of slow and embryonic (fast) myosin

Cite This Study

Vivarelli et al. (1988) studied Developmental pattern of slow myosin expression. Developmental stage (embryonic vs fetal myoblasts) was evaluated on Expression of slow and embryonic (fast) myosin. Embryonic myoblasts in mammals coexpress slow and embryonic (fast) myosin, whereas fetal myoblasts express only embryonic (fast) myosin.

synapsesocial.com/papers/6a96ae1aa8463d9029898acf https://doi.org/10.1083/jcb.107.6.2191

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The expression of slow myosin during mammalian somitogenesis and limb bud differentiation.

Discussion

Member takes

Implication

PICO

Cite This Study

The expression of slow myosin during mammalian somitogenesis and limb bud differentiation.

Discussion

Member takes

Implication

PICO

Cite This Study

Also Consider

Also Consider