Key result
Severe congenital heart defects were associated with a 17.4% 1-year mortality compared to 3.0% for nonsevere defects, though severe defect mortality decreased by 3.6% annually from 1994 to 2009.
Population
954,413 live births, stillbirths, and late-term abortions in Norway, 1994-2009
Design
Cohort
Follow-up
through 2012
Authors
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Mortality decline among live-born severe CHD may reflect increased terminations; leaves open whether overall fetal survival improved.
Cohort (n=954,413)
Yes
Absolute Event Rate: 17.4% vs 3%
The 1-year mortality of severe congenital heart defects among live births in Norway declined from 1994-2009, likely driven by increased termination of affected pregnancies and reduced operative mortality.
Jortveit et al. (2015) conducted a cohort in Congenital heart defects (n=954,413). Severe congenital heart defects vs. Nonsevere congenital heart defects was evaluated on 1-year cumulative mortality proportion. Severe congenital heart defects were associated with a 17.4% 1-year mortality compared to 3.0% for nonsevere defects, though severe defect mortality decreased by 3.6% annually from 1994 to 2009.
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