Key result
A modified Fisher grade of 3 to 4 was a strong predictor for in-hospital rebleeding ≤24 hours after aneurysmal subarachnoid hemorrhage (HR 4.4; 95% CI 2.1-10.6; P<0.001).
Why the study?
What are the clinical predictors for early rebleeding after aneurysmal subarachnoid hemorrhage?
Cohort (n=1,337)
No
What are the clinical predictors for early rebleeding after aneurysmal subarachnoid hemorrhage?
Hazard Ratio: 4.4 (95% CI 2.1–10.6)
Number Needed to Treat: 15
p-value: p=<0.001
Patients with aSAH and a modified Fisher grade of 3 to 4 are at high risk for early rebleeding within 24 hours, suggesting they may require emergent aneurysm repair.
No takes yet. Share an insight, caveat, or question.
May warrant closer monitoring in high-grade aSAH; leaves open whether it alters repair timing.
Bakker et al. (2015) conducted a cohort in Aneurysmal subarachnoid hemorrhage (aSAH) (n=1,337). Modified Fisher grade of 3 to 4 was evaluated on in-hospital rebleeding ≤24 hours after ictus (HR 4.4, 95% CI 2.1-10.6, p=<0.001). A modified Fisher grade of 3 to 4 was a strong predictor for in-hospital rebleeding ≤24 hours after aneurysmal subarachnoid hemorrhage (HR 4.4; 95% CI 2.1-10.6; P<0.001).
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