Key result
Pharmacologic therapy normalizes left ventricular function in >50% of peripartum cardiomyopathy patients, though subsequent pregnancies are almost always associated with recurrence.
Population
Pregnant females who develop peripartum cardiomyopathy, most commonly in the early postpartum period.
Design
Review
Authors
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Advise against subsequent pregnancies despite LV recovery; leaves open predictors of durable remission for prospective study.
Standard heart failure therapies and ICDs have improved survival and LV recovery in peripartum cardiomyopathy, but subsequent pregnancies pose a high risk of recurrence.
Murali et al. (2005) conducted a review in Peripartum cardiomyopathy. Pharmacologic therapy normalizes left ventricular function in >50% of peripartum cardiomyopathy patients, though subsequent pregnancies are almost always associated with recurrence.
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