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September 27, 2025JTCVS Open0 citationsOpen Access

Experience with Berlin heart support in children with a focus on device removal

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VIValerii IaprintsevIKIgor E. KonstantinovEBEdward Buratto

Key Result

Among pediatric patients supported by the Berlin Heart EXCOR, those with myocarditis were more likely to have a successful device removal (P=0.0003).

Study Design

Type

Observational

Multicenter

No

Structured PICO

P
Population
Consecutive infants and small children who underwent Berlin Heart EXCOR implantation at a single center from 2009 to 2024.
E
Exposure
Berlin Heart EXCOR implantation
O
Outcome
Outcomes of Berlin Heart EXCOR support and factors associated with successful device explantation

In pediatric patients on Berlin Heart EXCOR support, those with myocarditis are more likely to achieve myocardial recovery and successful device explantation, highlighting the need to evaluate for recovery prior to heart transplantation.

Main Result

p-value: p=0.0003

Abstract

Objective: The Berlin Heart EXCOR is the only durable ventricular assist device available for infants and small children. A subset of patients supported by the Berlin Heart EXCOR device experience cardiac recovery. This study aimed to evaluate the outcomes of Berlin Heart EXCOR support at our center and identify the factors associated with successful device explantation. Methods: This retrospective observational study included all consecutive patients who underwent Berlin Heart EXCOR implantation at the Royal Children's Hospital from 2009 to 2024. Results: .0003). Conclusions: . Patients with myocarditis are more likely to have a successful device removal. We believe that every patient must be evaluated for myocardial recovery and device removal before committing the patient to heart transplantation.

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Cite This Study

Iaprintsev et al. (2025) conducted an observational in Heart failure requiring ventricular assist device. Berlin Heart EXCOR support was evaluated on Successful device explantation (p=0.0003). Among pediatric patients supported by the Berlin Heart EXCOR, those with myocarditis were more likely to have a successful device removal (P=0.0003).

synapsesocial.com/papers/6a96c50c825a17a982578402https://doi.org/10.1016/j.xjon.2025.09.025
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