21 patients with vitiligo were treated by local application of 0.2% betamethasone 17-valerate in dimethyl sulfoxide (DMSO, 43% in a cream base) during 4 months. Symmetric patches were treated only with DMSO in the cream base. The results were very satisfactory and demonstrate that local application of betamethasone 17-valerate can induce repigmentation of vitiligo patches.
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Dorp et al. (2009) studied this question.