Key result
Obstetric and neonatological interventions, including magnesium sulfate, antenatal corticosteroids, delayed cord clamping, and therapeutic hypothermia, have proven or potentially protective effects on the risk of cerebral palsy.
Why the study?
Cerebral palsy imposes a major burden on caregivers and society, and there are documented and potentially protective prenatal and postnatal interventions that may reduce its risk.
Do prenatal and postnatal obstetric-neonatological interventions reduce the incidence of cerebral palsy in children?
Do prenatal and postnatal obstetric-neonatological interventions reduce the incidence of cerebral palsy in children?
Obstetric and neonatological interventions such as magnesium sulfate, delayed cord clamping, and therapeutic hypothermia should be part of good medical practice to reduce the risk of cerebral palsy.
Cerebral palsy is a disease that puts a great mental burden on caregivers and generates very high social costs. Children with CP require many years of rehabilitation and medical care. The etiology of the disease is undoubtedly multifactorial, and the pathogenesis is associated with focal damage to the central nervous system. One can find descriptions of well-documented interventions in the literature that reduce the risk of CP in certain groups of pregnant and neonatal patients, and interventions that have a potentially protective effect. In this review, we have analyzed the available literature in terms of prenatal and postnatal interventions that may have an impact on reducing the incidence of this condition in children.
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Młodawski et al. (2019) conducted a review in Cerebral palsy. Obstetric and neonatological interventions (e.g., magnesium sulfate, antenatal corticosteroids, delayed cord clamping, therapeutic hypothermia) was evaluated. Obstetric and neonatological interventions, including magnesium sulfate, antenatal corticosteroids, delayed cord clamping, and therapeutic hypothermia, have proven or potentially protective effects on the risk of cerebral palsy.
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