Size analysis and relationship of murine leukemia virus-specific mRNA's: evidence for transposition of sequences during synthesis and processing of subgenomic mRNA
Population
Mouse cells infected with Moloney murine leukemia virus (M-MuLV)
Design
Preclinical
Authors
Discussion
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Member takes
Implication
Provides initial evidence for splicing-like processing in M-MuLV; leaves open conservation across retroviruses.
Structured PICO
P
Population
Mouse cells infected with Moloney murine leukemia virus (M-MuLV)
I
Intervention
Electrophoresis in agarose gels followed by hybridization with M-MuLV-specific complementary DNA (cDNA)
O
Outcome
Detection and size analysis of virus-specific mRNAssurrogate
The study provides evidence for RNA splicing-like processes during the synthesis and processing of Moloney murine leukemia virus subgenomic mRNA.
Cite This Study
Fan et al. (1978) studied this question.