A capsulorhexis may be difficult to perform, in the absence of a red fundus reflexUsing 0.1 mL of trypan blue 0.1% to stain the anterior capsule in 30 patients with a mature cataract enabled us to visualize the capsulorhexis during phacoemulsification, No adverse reactions were observed up to 12 months after-surgery Trypan blue staining of the anterior capsule appears to be a safe technique to facilitate the performance of a capsulorhexis in the absence of a red fundus reflex. Patent pending far the dye (Vereenigde Octrooibureaux, The Hague). The Cornea Bank of the Netherlands Ophthalmic Research Institute,Amsterdam, and BIS/Eurotransplant, Leiden, The Netherlands, supplied the human eye-bank eyes; C C.J. van Vroonhoven, Department of Pathology, Erasmus University, Rotterdam, The Netherlands, provided valuable advice.
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Melles et al. (1999) studied this question.
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