Key result
Rituximab therapy was followed by the occurrence of enteroviral meningoencephalitis in two patients, a child with immune thrombocytopenia and an adult with relapsed B cell lymphoma.
Rituximab therapy may be associated with severe enteroviral infections such as meningoencephalitis due to B cell depletion.
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May warrant vigilance for enteroviral CNS infection with rituximab; leaves open causality and generalizability beyond case reports.
Quartier et al. (2003) studied this question. Rituximab therapy was followed by the occurrence of enteroviral meningoencephalitis in two patients, a child with immune thrombocytopenia and an adult with relapsed B cell lymphoma.
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