Key result
Left-to-right intracardiac shunts are associated with lower-than-expected peak dye dilution curve concentrations.
Why the study?
The effects of intracardiac shunts on the normal dye dilution curve were not previously described in detail.
Observational
The paper describes the effects of intracardiac shunts on normal dye dilution curves.
Answers are grounded in this paper and cite their sources.
May facilitate shunt detection via curve analysis; leaves open comparative value versus modern imaging.
In an earlier paper (Resnekov, 1962), the effects of valvular incompetence on the nomal dye dilution curve were described.This paper deals with the effects of intracardiac shunts on the normal dye curve.Broadbent et al. (1951) have shown that with a left-to-righit shunt, the peak concentration is lower than would be expected for the amount of dye injected (Fig. 1), the disappearance slope is z 0 la z z 0 TIME FIG.1.-Dye dilution curve, left-to-right shunt (reading right to left).The outline of a normal dye dilution curve is shown above the main figure.
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Leon Resnekov (1962) conducted an observational in Intracardiac shunts. Dye dilution curves vs. Normal dye curve was evaluated. In patients with left-to-right intracardiac shunts, the peak concentration on a dye dilution curve is lower than expected for the amount of dye injected.
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