Key result
Oleic acid stabilized Fe3O4/ethiodized-oil magnetic fluid demonstrated a saturation magnetization of 52.1 emu/g and a specific absorption rate of 50.16 W/g, heating from 25°C to 65°C in 650 s.
Oleic acid-stabilized Fe3O4/ethiodized-oil magnetic fluids demonstrate remarkable inductive heating effects, suggesting potential application in arterial embolization hyperthermia.
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Hypothesis-generating for embolization hyperthermia; animal data leave clinical translation open.
Fe3O4 nanoparticles (NPs) were prepared by the co‐precipitation of Fe3+ and Fe2+ with ammonium hydroxide, and were modified by four different surfactants. The modified Fe3O4 NPs were characterized by Fourier transform infrared spectroscopy, X‐ray powder diffraction, transmission electron microscopy and vibrating sample magnetometer. Then, the modified Fe3O4 NPs were dispersed in ethiodized‐oil by mechanical agitation and ultrasonic vibration to obtain stable Fe3O4/ethiodized‐oil magnetic fluids (MFs). The magnetic properties and rheological properties of the MFs were measured using a Gouy magnetic balance and a rotational rheometer, respectively. The saturation magnetization of the Fe3O4 modified by oleic acid was 52.1 emu/g. Furthermore, the result showed that the inductive heating effect of oleic acid stabilized Fe3O4/ethiodized‐oil MF was remarkable and it only took 650 s for the temperature rising from 25°C to 65°C. The specific absorption rate of the MF was 50.16 W/(g of Fe). It had a potential application in arterial embolization hyperthermia.
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Luo et al. (2012) studied this question. Fe3O4/ethiodized-oil magnetic fluids was evaluated on Saturation magnetization and inductive heating effect. Oleic acid stabilized Fe3O4/ethiodized-oil magnetic fluid demonstrated a saturation magnetization of 52.1 emu/g and a specific absorption rate of 50.16 W/g, heating from 25°C to 65°C in 650 s.
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