Why the study?
Does autonomic neuropathy increase mortality in patients with insulin-dependent diabetes mellitus?
Population
506 randomly selected patients with insulin-dependent diabetes mellitus screened for autonomic neuropathy…
Comparison
Presence of autonomic neuropathy (exposure) vs Normal autonomic function
Design
Cohort
Follow-up
5 years
Authors
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Autonomic neuropathy was associated with high mortality in insulin-dependent diabetes; leaves open whether screening or targeted interventions improve survival.
Does autonomic neuropathy increase mortality in patients with insulin-dependent diabetes mellitus?
Autonomic neuropathy is a major independent predictor of 5-year mortality, particularly from renal failure, in patients with insulin-dependent diabetes mellitus.
O'Brien et al. (1991) studied this question.
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