Key result
Abnormal cardiovascular reflex tests in Type 2 diabetes were associated with lower 8-year survival compared to normal tests (74.5% vs 85.4% without postural hypotension).
Why the study?
Do abnormal cardiovascular reflex tests predict mortality in patients with Type 2 diabetes mellitus?
Cohort (n=612)
Do abnormal cardiovascular reflex tests predict mortality in patients with Type 2 diabetes mellitus?
Abnormal cardiovascular reflex tests, especially when combined with postural hypotension, are significant predictors of increased mortality in patients with Type 2 diabetes.
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May support prognostic stratification in type 2 diabetes; leaves open whether testing improves outcomes.
Chen et al. (2001) conducted a cohort in Type 2 diabetes mellitus (n=612). Abnormal cardiovascular reflex (CVR) tests vs. Normal CVR tests was evaluated on 8-year survival rate. Abnormal cardiovascular reflex tests in Type 2 diabetes were associated with lower 8-year survival compared to normal tests (74.5% vs 85.4% without postural hypotension).
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