Population
Patients with atherosclerotic carotid artery disease based on carotid endarterectomy surgical specimens
Design
Review
Key result
Plaque disruption and intraplaque hemorrhage occur significantly more frequently in symptomatic compared with asymptomatic carotid endarterectomy specimens, suggesting they initiate symptoms.
Authors
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Plaque disruption and intraplaque hemorrhage are key mechanisms in the transition of asymptomatic carotid atherosclerosis to symptomatic disease, drawing parallels to coronary artery pathology.
Plaque disruption and intraplaque hemorrhage are key mechanisms in the transition of asymptomatic carotid atherosclerosis to symptomatic disease, drawing parallels to coronary artery pathology.
Fisher et al. (1987) conducted a review in Atherosclerotic carotid artery disease. Plaque disruption (ulceration) and intraplaque hemorrhage vs. Asymptomatic carotid arteries was evaluated on Frequency of plaque disruption and hemorrhage in symptomatic vs asymptomatic endarterectomy specimens. Plaque disruption and intraplaque hemorrhage occur significantly more frequently in symptomatic compared with asymptomatic carotid endarterectomy specimens, suggesting they initiate symptoms.