Key result
In asymptomatic patients late after arterial switch operation, 3D echocardiography detected subclinical left ventricular remodeling with significantly higher end-diastolic volumes compared to healthy references from age 9 onwards (79.61 vs 53.52 ml for ages 9-12, p<0.001).
Why the study?
To evaluate left ventricle function and remodeling using 3D echocardiography in patients who underwent an arterial switch procedure for transposition of the great arteries in long-term follow-up.
Does three-dimensional echocardiography detect subclinical left ventricular remodeling in asymptomatic patients late after arterial switch operation for transposition of the great arteries?
Population
54 asymptomatic patients after single-stage ASO for TGA with normal LVEF
Comparison
ASO patients vs healthy peers or reference values
Design
Cross-sectional comparative study
Authors
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May support 3D echo surveillance for subclinical LV changes post-ASO; hypothesis-generating without prognostic data.
Cross-Sectional (n=54)
No
Does three-dimensional echocardiography detect subclinical left ventricular remodeling in asymptomatic patients late after arterial switch operation for transposition of the great arteries?
Absolute Event Rate: 79.61% vs 53.52%
p-value: p=<0.001
Three-dimensional echocardiography can detect subclinical left ventricular remodeling, such as increased LV dimensions, in asymptomatic children and young adults late after arterial switch operation.
Bartolacelli et al. (2020) conducted a cross-sectional in Transposition of the great arteries (TGA) after arterial switch operation (ASO) (n=54). Arterial switch operation (ASO) vs. Healthy reference values was evaluated on 3D left ventricular end-diastolic volume (LVEDV) in patients aged 9-12 years (p=<0.001). In asymptomatic patients late after arterial switch operation, 3D echocardiography detected subclinical left ventricular remodeling with significantly higher end-diastolic volumes compared to healthy references from age 9 onwards (79.61 vs 53.52 ml for ages 9-12, p<0.001).
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