Key result
Prenatal foramen ovale diameter ≤6 mm (AUC 0.764) and VSD diameter ≤3.2 mm (AUC 0.728) predicted the need for postnatal urgent balloon atrial septostomy (p<0.05).
Why the study?
To analyze prenatal and postnatal outcomes in fetuses with d-TGA and determine whether prenatal echocardiography predicts the need for postnatal urgent balloon atrial septostomy.
Can prenatal echocardiographic measurements of the foramen ovale and ventricular septal defect predict the need for postnatal urgent balloon atrial septostomy in fetuses with d-TGA?
Population
48 fetuses with d-TGA confirmed postnatally
Comparison
Postnatal urgent BAS vs non-urgent BAS
Design
Retrospective single-center study
Authors
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May support prenatal risk stratification for urgent BAS in d-TGA; leaves open need for prospective validation before clinical adoption.
Cohort (n=48)
No
Can prenatal echocardiographic measurements of the foramen ovale and ventricular septal defect predict the need for postnatal urgent balloon atrial septostomy in fetuses with d-TGA?
p-value: p=<0.05
Prenatal echocardiographic measurement of the foramen ovale and ventricular septal defect diameters can help predict the need for urgent postnatal balloon atrial septostomy in fetuses with d-TGA.
Gezer et al. (2023) conducted a cohort in d-TGA (Transposition of the great arteries) (n=48). Prenatal echocardiography (foramen ovale and VSD diameter) was evaluated on Postnatal urgent balloon atrial septostomy (BAS) (p=<0.05). Prenatal foramen ovale diameter ≤6 mm (AUC 0.764) and VSD diameter ≤3.2 mm (AUC 0.728) predicted the need for postnatal urgent balloon atrial septostomy (p<0.05).