Key result
Complete transposition of the great arteries was associated with more severe pulmonary vascular disease after five months of age compared to ventricular septal defect, with medial thickness being only 70%.
Population
62 autopsy cases, including 40 cases of complete transposition of the great arteries and 22 cases of…
Design
Cross-sectional
Authors
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TGA may warrant earlier pulmonary vascular surveillance than VSD after infancy; leaves open whether medial thinning drives progression.
Observational (n=62)
Suppression of medial hypertrophy in response to high pulmonary pressure in TGA may precipitate severe pulmonary vascular disease compared to VSD.
Yamaki et al. (1976) conducted an observational in Complete transposition of the great arteries and ventricular septal defect (n=62). Complete transposition of the great arteries (TGA) vs. Ventricular septal defect (VSD) was evaluated on Index of pulmonary vascular disease (IPVD) and medial thickness. Complete transposition of the great arteries was associated with more severe pulmonary vascular disease after five months of age compared to ventricular septal defect, with medial thickness being only 70%.
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