Key result
Left ventricular hypertrophy in silent myocardial ischemia was associated with significantly higher left ventricular filling pressure at peak exercise (19 +/- 7 vs 11 +/- 3 mmHg; p < 0.01).
Why the study?
Does the presence of left ventricular hypertrophy affect left ventricular filling dynamics during dynamic exercise in patients with silent myocardial ischemia?
Observational (n=20)
Does the presence of left ventricular hypertrophy affect left ventricular filling dynamics during dynamic exercise in patients with silent myocardial ischemia?
Absolute Event Rate: 19% vs 11%
p-value: p=< 0.01
Patients with silent myocardial ischemia and coexistent left ventricular hypertrophy exhibit severely abnormal left ventricular filling dynamics during exercise despite the absence of ischemic chest pain.
Authors
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May warrant exercise diastolic assessment in silent ischemia with LVH; leaves open whether hypertrophy independently drives filling pressure elevation.
Yokota et al. (1994) conducted an observational in Silent myocardial ischemia (n=20). Left ventricular hypertrophy vs. Absence of left ventricular hypertrophy was evaluated on Left ventricular filling pressure at peak exercise (p=< 0.01). Left ventricular hypertrophy in silent myocardial ischemia was associated with significantly higher left ventricular filling pressure at peak exercise (19 +/- 7 vs 11 +/- 3 mmHg; p < 0.01).
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