ATP-sensitive K+ channels in hypertrophied feline ventricular myocytes require higher ATP concentrations for half-maximal inhibition compared to normal myocytes, which may provide a protective function during metabolic stress.
No takes yet. Share an insight, caveat, or question.
Hypothesis-generating for KATP channel protection in hypertrophy; leaves open translation to human disease.
Cameron et al. (1988) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: