What question did this study set out to answer?

Provide updated clinical recommendations regarding the epidemiology, prevention, and therapeutic management of ventricular assist device infections in solid organ transplant candidates.

March 29, 2019Clinical Transplantation

Ventricular assist device‐related infections and solid organ transplantation—Guidelines from the American Society of Transplantation Infectious Diseases Community of Practice

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Provide updated clinical recommendations regarding the epidemiology, prevention, and therapeutic management of ventricular assist device infections in solid organ transplant candidates.
Evidence-based guideline synthesis conducted by the American Society of Transplantation Infectious Diseases Community of Practice, updating previous guidance established since 2004.
Comprehensive evaluation of clinical data regarding device infection epidemiology, anatomic involvement, and pre- and post-transplant management protocols.
Nearly 50% of candidates awaiting heart transplantation require mechanical circulatory support, with device-associated infections contributing significantly to increased wait-list mortality.
Complete explantation of all ventricular assist device components at the time of heart transplantation provides a definitive cure for device-associated infections.
Patients presenting with active pre-existing device infections achieve favorable post-transplant survival when managed with structured post-transplant antimicrobial strategies.

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Implication

Clinical practice guideline outlines management strategies for device infections in heart transplant candidates, highlighting full device explantation as a definitive cure.

Cite This Study

Koval et al. (2019) studied this question.

synapsesocial.com/papers/6a96fd2bc00de92d9bfbdbdc https://doi.org/10.1111/ctr.13552

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Implication

Clinical practice guideline outlines management strategies for device infections in heart transplant candidates, highlighting full device explantation as a definitive cure.

Ventricular assist device‐related infections and solid organ transplantation—Guidelines from the American Society of Transplantation Infectious Diseases Community of Practice

Key Points

Discussion

Implication

Cite This Study

Ventricular assist device‐related infections and solid organ transplantation—Guidelines from the American Society of Transplantation Infectious Diseases Community of Practice

Key Points

Discussion

Implication

Cite This Study

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