Synthese und Eigenschaften von 6‐Desoxy‐6‐halogen‐Derivaten der L ‐Ascorbinsäure

Synthesis and Properties of 6‐Deoxy‐6‐halogeno‐Derivatives of L‐Ascorbic Acid 6‐Deoxy‐6‐chloro‐, ‐6‐bromo‐, ‐6‐iodo‐ and ‐6‐fluoro derivatives of L‐ascorbic acid have been synthesized and characterized. The physiological properties of the chloro derivative have been investigated. It shows a high antiscurvy activity. The chloro‐ and bromo‐derivatives have been reduced to the corresponding deoxy compound, which is an interesting chiral intermediate for the preparation of rare ω‐deoxy sugars.