Key result
Postoperative JET linked to ~75% higher complication rates and increased mortality after TOF repair.
Why the study?
Postoperative junctional ectopic tachycardia is a potentially life-threatening arrhythmia after congenital heart surgery, particularly TOF repair, that can cause hemodynamic instability due to atrioventricular dissociation.
What are the incidence, risk factors, and outcomes of junctional ectopic tachycardia after tetralogy of Fallot repair in pediatric patients?
Cohort (n=114)
No
What are the incidence, risk factors, and outcomes of junctional ectopic tachycardia after tetralogy of Fallot repair in pediatric patients?
Absolute Event Rate: 73.7% vs 42.1%
p-value: p=0.02
Postoperative junctional ectopic tachycardia occurs in approximately 17% of pediatric patients following tetralogy of Fallot repair and is associated with significantly increased morbidity and mortality.
JET after TOF repair prolongs ventilation and ICU stay; leaves open optimal preventive strategies in high-risk infants.
Background: Postoperative junctional ectopic tachycardia (JET) is a potentially life-threatening arrhythmia that may occur after congenital heart surgery, especially following tetralogy of Fallot (TOF) repair. It can cause hemodynamic instability due to atrioventricular dissociation. This study aimed to evaluate the incidence, risk factors, and outcomes of JET after TOF repair, with particular focus on management strategies and the impact of JET duration on recovery. Methods: This retrospective study included 114 pediatric patients who underwent TOF repair between 2015 and 2023. The study was approved by the institutional ethics committee (File No: 2023/09-31, Date: 10 October 2023). Postoperative JET was diagnosed based on standard electrocardiographic criteria. Perioperative variables, surgical techniques, and postoperative outcomes were analyzed. Results: JET occurred in 19 patients (16.7%). Compared with patients without JET, those with JET had higher complication rates (73.7% vs. 42.1%, p = 0.02), prolonged inotropic support, and increased mortality (15.8% vs. 2.1%, p = 0.024). Ionized calcium (p < 0.001) and pH levels (p < 0.037) were significantly lower in JET patients. Right ventricular outflow tract muscle resection was strongly associated with JET occurrence (p = 0.003). Although cardiopulmonary bypass and aortic cross-clamp times did not predict JET, both correlated with JET duration (p < 0.05). Conclusions: Postoperative JET remains a major concern following TOF repair, leading to adverse outcomes and longer recovery. Optimizing perioperative management may help reduce JET-related complications, though further multicenter prospective studies are needed to confirm these findings.
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Durak et al. (2025) conducted a cohort in Tetralogy of Fallot (n=114). Postoperative junctional ectopic tachycardia vs. No postoperative junctional ectopic tachycardia was evaluated on Complication rates (p=0.02). Postoperative junctional ectopic tachycardia after tetralogy of Fallot repair was associated with higher complication rates (73.7% vs. 42.1%, p=0.02) and increased mortality (15.8% vs. 2.1%, p=0.024).
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