Key result
A modified flow measurement method demonstrated decreased fibrin gel permeability in MI patients compared to controls and increased permeability in healthy individuals after acetylsalicylic acid therapy.
Why the study?
Does a modified flow measurement method accurately and reproducibly determine fibrin gel permeability in clinical samples?
Population
Plasma samples from patients with previous myocardial infarction and 10 healthy individuals
Comparison
Modified flow measurement method for fibrin gel… vs Previous method; healthy controls; before…
Design
Other
Authors
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May aid assessment of clot stability in MI; leaves open clinical utility pending larger validation studies.
Does a modified flow measurement method accurately and reproducibly determine fibrin gel permeability in clinical samples?
A simplified, low-volume flow measurement method for fibrin gel permeability is highly reproducible and can detect changes in clot stability associated with cardiovascular disease and antiplatelet therapy.
He et al. (2005) studied Myocardial infarction. Modified flow measurement method vs. Controls / Before therapy was evaluated on Fibrin gel permeability (Darcy constant, Ks). A modified flow measurement method demonstrated decreased fibrin gel permeability in MI patients compared to controls and increased permeability in healthy individuals after acetylsalicylic acid therapy.
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