Key result
Landiolol significantly decreased mean heart rate from 206.1 to 158.0 beats/min within 2 hours (p<0.01) in pediatric patients with postoperative junctional ectopic tachycardia.
Why the study?
Does landiolol hydrochloride reduce heart rate in pediatric patients with junctional ectopic tachycardia after open-heart surgery?
Observational (n=10)
No
Does landiolol hydrochloride reduce heart rate in pediatric patients with junctional ectopic tachycardia after open-heart surgery?
Absolute Event Rate: 158% vs 206.1%
p-value: p=<0.01
Landiolol rapidly and safely reduces heart rate in pediatric patients with postoperative junctional ectopic tachycardia, facilitating atrioventricular sequential pacing and restoration of sinus rhythm.
May support landiolol for rate control in children with postoperative junctional ectopic tachycardia; leaves open randomized confirmation.
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Yoneyama et al. (2018) conducted an observational in Junctional ectopic tachycardia after pediatric heart surgery (n=10). Landiolol hydrochloride vs. Pre-administration baseline was evaluated on Mean heart rate (p=<0.01). Landiolol significantly decreased mean heart rate from 206.1 to 158.0 beats/min within 2 hours (p<0.01) in pediatric patients with postoperative junctional ectopic tachycardia.
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