Key result
Continuous intravenous landiolol infusion successfully converted 25.0% of pediatric patients with supraventricular tachycardia to normal sinus rhythm within 210 minutes.
Why the study?
Junctional ectopic tachycardia after surgery for CHD is a serious arrhythmia causing increased morbidity and mortality, with limited treatment data after sepsis.
May support landiolol for pediatric postoperative JET; leaves open efficacy in prospective SVT trials.
Junctional ectopic tachycardia, after surgery for CHD, is a serious arrhythmia that can cause increased morbidity and mortality. We report a case of junctional ectopic tachycardia, preceded by sepsis, in a 4-year-old girl, 31 months after open-heart surgery. She was successfully treated using low-dose landiolol hydrochloride.
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Oka et al. (2015) studied Supraventricular tachycardia (SVT) (n=60). Landiolol was evaluated on Conversion to normal sinus rhythm within 210 min of the commencement of landiolol infusion (95% CI 14.0; 35.9). Continuous intravenous landiolol infusion successfully converted 25.0% of pediatric patients with supraventricular tachycardia to normal sinus rhythm within 210 minutes.
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