Key result
Obstructive sleep apnoea severity was independently associated with higher total cholesterol (P<0.001 across ODI quartiles) and lower HDL cholesterol (P=0.002 for highest vs lowest AHI quartile).
Population
Patients enrolled in the European Sleep Apnea Database cohort, mean apnoea-hypopnoea index: 25.7 ± 25.9…
Design
Cohort
Authors
Loading...
May support lipid screening in severe OSA; hypothesis-generating for causal effects and treatment trials.
Cohort
Yes
p-value: p=< 0.001
Obstructive sleep apnoea severity is independently associated with adverse lipid profiles, including higher total cholesterol and lower HDL cholesterol.
Gündüz et al. (2018) conducted a cohort in Obstructive sleep apnoea. Obstructive sleep apnoea severity vs. Lower severity of obstructive sleep apnoea was evaluated on Plasma lipid concentrations (total cholesterol, HDL-C, LDL-C, and fasting triglycerides) (p=< 0.001). Obstructive sleep apnoea severity was independently associated with higher total cholesterol (P<0.001 across ODI quartiles) and lower HDL cholesterol (P=0.002 for highest vs lowest AHI quartile).
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: