Population
Circularly oriented strips of the bladder neck muscle of sheep (in vitro model)
Comparison
Electrical field stimulation and pharmacological… vs Absence of drugs or presence of reversal agents
Design
Preclinical
Authors
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Highlights potential NO pathway in bladder neck control; leaves open translation to human lower urinary tract disorders.
This preclinical study demonstrates that nitric oxide mediates non-adrenergic, non-cholinergic nerve-evoked relaxation of the sheep urinary bladder neck.
Thornbury et al. (1992) studied this question.
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