Key result
High resolution carotid ultrasonography demonstrated a 97% correlation with surgical specimens, compared to 70% for angiography, in identifying carotid atherosclerotic lesions.
Why the study?
Does high resolution carotid ultrasonography improve diagnostic accuracy compared to angiography for identifying carotid atherosclerotic plaques and stenosis?
Observational (n=37)
Does high resolution carotid ultrasonography improve diagnostic accuracy compared to angiography for identifying carotid atherosclerotic plaques and stenosis?
Answers are grounded in this paper and cite their sources.
High resolution carotid ultrasonography demonstrated significantly higher diagnostic accuracy (97%) compared to angiography (70%) when correlated with surgical specimens, suggesting it should replace angiography as the reference standard.
Atherosclerotic plaques and high grade stenosis in the carotid circulation are responsible for symptoms of cerebral and retinal ischemia. Identification of these lesions by angiography has been the "gold standard" for which the decision of endarterectomy depended. The recent introduction of high resolution carotid ultrasonography has allowed us to compare thirty-seven surgical specimens with the results of preoperative screening with angiography. UCI had a 97% correlation whereas angiography was accurate only 70%. More importantly there were ten negative angiograms in patients with clinically active ulcerative plaque disease. If surgery were based solely on the angiographic appearance of ulcerative plaques or high grade stenosis, then less than half of the patients have received the correct treatment. UCI deserves to be considered the new reference standard.
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Weintraub et al. (1985) conducted an observational in Carotid atherosclerotic plaques and high grade stenosis (n=37). High resolution carotid ultrasonography vs. Angiography was evaluated on Correlation with surgical specimens. High resolution carotid ultrasonography demonstrated a 97% correlation with surgical specimens, compared to 70% for angiography, in identifying carotid atherosclerotic lesions.
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