Why the study?
Does the use of pulsatile flow and a simple flow control method in centrifugal pumps improve pump performance and reduce hemolysis compared to a roller pump in an in vitro model?
Does the use of pulsatile flow and a simple flow control method in centrifugal pumps improve pump performance and reduce hemolysis compared to a roller pump in an in vitro model?
The Terumo Capiox centrifugal pump with pulsatile flow demonstrated less hemolysis than a roller pump in an in vitro model, and a step-wise clamping method provided stable flow control, suggesting potential for expanded use in open heart surgery.
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Lower hemolysis with Terumo Capiox in vitro; hypothesis-generating for centrifugal pumps and should not yet change surgical practice.
To expand the usage of the centrifugal pump (CP) in open heart surgery, we performed two studies. In the first, we evaluated pulsatile flow in the CP. In vitro pump performance of the Terumo Capiox pump (TCP) and the Sarns Delphin pump (SDP) and increase of free hemoglobin (mg/dl) after driving 6 h were investigated using bovine blood. A roller pump (RP) was used as a comparison. Equally effective pulsatile flow was obtained in both CPs. Hemolysis was less severe in TCP (120 mg/dl) than SDP (210 mg/dl) and RP (320 mg/dl). In the second study, we evaluated a simple flow control method. Flow rate was easily controlled with step-wise clamping of 3-pronged tubing (Triple-flow) without changing rotational speed, regardless of afterload. Fluctuation of flow was much less with this method than with the rotational speed change method. The use of pulsatile flow of TCP, with its minimum increase of hemolysis and the easier flow control method during the weaning process, may expand the usage of CP in open heart surgery.
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Nishida et al. (1994) studied this question.
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