Key result
Thin-section CT findings of air trapping before the clinical appearance of bronchiolitis obliterans syndrome had a sensitivity of 50% and specificity of 80%, limiting its value as a screening test.
Why the study?
Can thin-section CT findings predict bronchiolitis obliterans syndrome in lung transplant recipients before its clinical appearance?
Case-Control (n=52)
Can thin-section CT findings predict bronchiolitis obliterans syndrome in lung transplant recipients before its clinical appearance?
Effect estimate: Sensitivity 50%, Specificity 80%
Thin-section CT has limited value as a screening test for predicting bronchiolitis obliterans syndrome before its clinical appearance in lung transplant recipients.
No takes yet. Share an insight, caveat, or question.
Thin-section CT air trapping has limited screening utility for pre-clinical BOS; leaves open the need for better predictive biomarkers in lung transplant recipients.
Konen et al. (2004) conducted a case-control in Bronchiolitis obliterans syndrome in lung transplant recipients (n=52). Thin-section CT findings (air trapping, mosaic perfusion, bronchiectasis, bronchial wall thickening) vs. Matched controls without bronchiolitis obliterans syndrome was evaluated on Prediction of bronchiolitis obliterans syndrome before clinical appearance using air trapping (Sensitivity 50%, Specificity 80%). Thin-section CT findings of air trapping before the clinical appearance of bronchiolitis obliterans syndrome had a sensitivity of 50% and specificity of 80%, limiting its value as a screening test.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: