Key result
Small molecules targeting highly conserved noncoding RNA elements in viral genomes offer a promising strategy for developing antiviral therapies against pathogens like HIV, HCV, and SARS-CoV.
Design
Review
Authors
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Supports RNA-targeted antivirals in preclinical models; leaves open clinical translation without prospective trials.
Targeting highly conserved noncoding RNA elements in viral genomes with small molecules offers a promising strategy for developing novel antiviral therapies.
Thomas Hermann (2016) conducted a review in Viral infections. Small molecules targeting viral RNA was evaluated. Small molecules targeting highly conserved noncoding RNA elements in viral genomes offer a promising strategy for developing antiviral therapies against pathogens like HIV, HCV, and SARS-CoV.
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