Key result
Acute myocardial infarction is associated with the appearance of up to 14 CK-MM subbands, which reach maximum intensity 3-12 hours post-infarction due to secondary conversion.
Why the study?
What are the temporal changes and heterogeneity of serum CK-MM subbands following acute myocardial infarction?
Population
Sera from patients with acute myocardial infarction (AMI) and normal serum
Comparison
Isoelectric focusing and nonequilibrium pH… vs Normal serum
Design
Other
Follow-up
Up to 36 hours post-infarction
Authors
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May support AMI timing via CK-MM patterns; leaves open diagnostic role versus modern troponin assays.
Observational
What are the temporal changes and heterogeneity of serum CK-MM subbands following acute myocardial infarction?
The complexity of CK-MM patterns post-AMI is explained by a secondary conversion of normal to abnormal subbands superimposed upon anodal conversion.
Williams et al. (1989) conducted an observational in Acute myocardial infarction. Acute myocardial infarction vs. Normal serum was evaluated on Presence and conversion of CK-MM subbands. Acute myocardial infarction is associated with the appearance of up to 14 CK-MM subbands, which reach maximum intensity 3-12 hours post-infarction due to secondary conversion.
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