July 1, 2016European Journal of Preventive Cardiology
Impact of exercise-based cardiac rehabilitation on long-term clinical outcomes in patients with left main coronary artery stenosis
Key result
Exercise-based cardiac rehabilitation was associated with a significant decrease in mortality among patients with left main coronary artery stenosis (HR 0.62; 95% CI 0.43-0.89; p=0.009).
Why the study?
Does exercise-based cardiac rehabilitation reduce mortality in patients with left main coronary artery stenosis?
Population
3,120 patients with left main coronary artery stenosis
Comparison
Exercise-based cardiac rehabilitation program vs No cardiac rehabilitation
Design
Cohort
Follow-up
7 years
Authors
Discussion
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Member takes
Implication
May support exercise-based cardiac rehabilitation in left main stenosis; leaves open need for randomized confirmation.
Study Design
Type
Cohort (n=3,120)
Structured PICO
Does exercise-based cardiac rehabilitation reduce mortality in patients with left main coronary artery stenosis?
P
Population
3,120 patients with left main coronary artery stenosis from a prospective registry, followed for 7 years.
E
Exposure
Exercise-based cardiac rehabilitation program
C
Comparator
No cardiac rehabilitation
O
Outcome
Mortality at 7 yearshard clinical
Main Result
Hazard Ratio: 0.62 (95% CI 0.43–0.89)
p-value: p=0.009
Exercise-based cardiac rehabilitation is associated with significantly reduced long-term mortality in patients with left main coronary artery stenosis.
Cite This Study
Lee et al. (2016) conducted a cohort in Left main coronary artery stenosis (n=3,120). Exercise-based cardiac rehabilitation vs. Non-rehabilitation was evaluated on Mortality (HR 0.62, 95% CI 0.43-0.89, p=0.009). Exercise-based cardiac rehabilitation was associated with a significant decrease in mortality among patients with left main coronary artery stenosis (HR 0.62; 95% CI 0.43-0.89; p=0.009).