A Case of Rendu-Osler-Weber Disease with Bleeding from Mucosal Telangiectasia of the Stomach Treated by Endoscopic Hemostasis Using Clip

A case of 53-year-old female was reported who admitted to our clinic with the chief complaint of epistaxis and melena. She had been treated with pulmonary arteriovenous fistulae and heart failure caused by Rendu-Osler-Weber disease. Endoscopic observation revealed multiple small elevated lesion of teleangiectasia and one lesion with bleeding on the wall of the stomach. Hemostatic technique using clip was performed and bleeding was stopped. There were no noteworthy complications. No bleeding from other teleangiectasia has occurred after the treatment. Pulmonary arteriovenous fistulae may involve brain complications such as abscess and embolism, then surgical resection should be performed. Moreover, patients with recurrent hemorrhage from teleangiectasia with anemia should be treated with non-operative manner. We conclude that endoscopic hemostasis using clip is a safe and effective treatment for bleeding from teleangiectasia of Rendu-Osler-Weber disease.