Key result
Prenatal diagnosis of coarctation of the aorta was associated with lower mortality compared to severe postnatal diagnosis (18.6% mortality in the severe postnatal group; p=0.005).
Why the study?
Does prenatal diagnosis of coarctation of the aorta improve neonatal outcomes and reduce mortality compared to postnatal diagnosis?
Population
115 neonates with coarctation of the aorta, including 38 diagnosed prenatally and 77 diagnosed postnatally…
Comparison
Prenatal diagnosis of coarctation of the aorta vs Postnatal diagnosis of coarctation of the aorta
Design
Cohort
Follow-up
Neonatal period
Authors
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Supports prenatal diagnosis for lower coarctation mortality; leaves open prospective confirmation before screening changes.
Cohort (n=115)
Does prenatal diagnosis of coarctation of the aorta improve neonatal outcomes and reduce mortality compared to postnatal diagnosis?
p-value: p=0.005
Prenatal diagnosis of severe coarctation of the aorta is associated with lower prostaglandin doses and reduced neonatal mortality compared to postnatal diagnosis.
Słodki et al. (2018) conducted a cohort in Coarctation of the aorta (CoA) (n=115). Prenatal diagnosis vs. Postnatal diagnosis was evaluated on Mortality rate (p=0.005). Prenatal diagnosis of coarctation of the aorta was associated with lower mortality compared to severe postnatal diagnosis (18.6% mortality in the severe postnatal group; p=0.005).
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