Key result
A normal rapid ELISA VIDAS D-dimer test as a stand-alone test safely excludes DVT and PE with a negative predictive value of 99 to 100%, reducing the need for noninvasive imaging by 40 to 50%.
Why the study?
Do rapid D-dimer assays safely exclude venous thromboembolism in outpatients with suspected DVT or PE?
Population
Outpatients with suspected deep vein thrombosis (DVT) and pulmonary embolism (PE)
Design
Review
Authors
Loading...
May allow fewer imaging tests for outpatients with suspected VTE; leaves open need for prospective validation.
Do rapid D-dimer assays safely exclude venous thromboembolism in outpatients with suspected DVT or PE?
A rapid ELISA D-dimer test can safely exclude DVT and PE with high negative predictive value, significantly reducing the need for imaging in outpatients.
Michiels et al. (2006) conducted a review in Suspected Deep Vein Thrombosis and Pulmonary Embolism. Rapid D-dimer assays (ELISA, turbidimetric, agglutination) was evaluated on Negative predictive value for DVT and PE exclusion. A normal rapid ELISA VIDAS D-dimer test as a stand-alone test safely excludes DVT and PE with a negative predictive value of 99 to 100%, reducing the need for noninvasive imaging by 40 to 50%.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: