Why the study?
Does sirolimus-eluting stent (SES) compared to biolimus-eluting stents (BES) increase coronary vasoconstriction and vasa vasorum formation in pigs?
Does sirolimus-eluting stent (SES) compared to biolimus-eluting stents (BES) increase coronary vasoconstriction and vasa vasorum formation in pigs?
Adventitial vasa vasorum formation and Rho-kinase expression are implicated in abnormal coronary hyperconstriction after drug-eluting stent implantation, with differences observed between stent polymer types.
Large vessels, including the coronary arteries, have their own vascular system within the adventitia in the form of network of small vessels, which are called the vasa vasorum. Under physiological conditions, the vasa vasorum transport blood cells, nourishment, oxygen, and various molecules to the adventitia. Recently, the role of the vasa vasorum in the development of atherosclerosis has been receiving consider-B
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Shimohama et al. (2015) conducted an editorial in Coronary vasospasm after drug-eluting stent implantation. Drug-eluting stents (Sirolimus-eluting vs Biolimus-eluting) was evaluated.
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