Population
Aorta of man and dog (preclinical models)
Design
Review
Authors
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Vasa vasorum dysfunction may contribute to aortic disease; leaves open targeted interventions pending prospective validation.
Vasa vasorum play a critical role in nourishing the outer layers of the aortic media, and their dysfunction may contribute to aortic diseases like medial necrosis and atherosclerosis.
Heistad et al. (2008) studied this question.
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