Population
Isolated hamster hearts
Comparison
Perfusion with [1,3-3H]glycerol in the presence… vs Control (implied, perfusion without lidocaine)
Design
Preclinical
Authors
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Should not change lidocaine use; hypothesis-generating for its effects on cardiac phospholipid metabolism.
Lidocaine modulates cardiac phospholipid biosynthesis through both direct and indirect effects on biosynthetic enzymes in an isolated hamster heart model.
Wong et al. (1994) studied this question.
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