Key result
Autopsy findings in 43 cases of endomyocardial fibroelastosis revealed thickening of the ventricular mural endocardium and valve malformations without other associated developmental anomalies.
Observational (n=43)
Yes
This historical report characterizes the specific pathological findings of endomyocardial fibroelastosis, distinguishing it from other congenital heart malformations.
Answers are grounded in this paper and cite their sources.
Supports EFE pathologic distinction from other anomalies; leaves open correlation with modern imaging in living patients.
Craig1in 1949 reported autopsy findings in 43 cases of a congenital heart disease characterized by thickening of the ventricular mural endocardium and a thick malformation of the valves in the majority of the cases. The hearts studied comprised the autopsy material at the Boston Children's Hospital from 1928 to 1948 and at the Boston Lying-In Hospital from 1932 until 1949. This type of heart abnormality in the past has been separated from the general group of congenital heart malformations because of the belief that they have their origin in an inflammatory process during the period of gestation. They have been considered as instances of "fetal endocarditis." Craig1stresses the fact that in these cases associated developmental anomalies both within the heart and in the remainder of the body were "conspicuously" absent. The subendocardial changes in the myocardium were quite specific for this type of cardiac malformation, none
No takes yet. Share an insight, caveat, or question.
A 1954 study conducted an observational in Endomyocardial fibroelastosis (n=43). Endomyocardial fibroelastosis was evaluated on Autopsy findings. Autopsy findings in 43 cases of endomyocardial fibroelastosis revealed thickening of the ventricular mural endocardium and valve malformations without other associated developmental anomalies.
Synapse has enriched 10 related papers. Consider them for comparative context: