Key result
Small mechanical mitral valve replacement in children under 5 years showed durable hemodynamics, with overall freedom from death or valve replacement of 82.6% at 5 years and 75.7% at 10 years.
Why the study?
Does small mechanical mitral valve replacement improve freedom from death or valve replacement in children under 5 years of age?
Cohort (n=24)
Does small mechanical mitral valve replacement improve freedom from death or valve replacement in children under 5 years of age?
Despite high early mortality, small mechanical mitral valve prostheses in children under 5 years of age perform remarkably well, providing durable hemodynamics and typically lasting over 8 years before requiring replacement.
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May support mechanical mitral replacement in select young children; leaves open randomized comparisons to alternatives.
Vohra et al. (2006) conducted a cohort in Mitral valve replacement (n=24). Small mechanical mitral valve replacement was evaluated on Overall freedom from death or valve replacement at 5 years. Small mechanical mitral valve replacement in children under 5 years showed durable hemodynamics, with overall freedom from death or valve replacement of 82.6% at 5 years and 75.7% at 10 years.
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