Key result
FDG PET/CT detected pulmonary lymphangitic carcinomatosis with 86% sensitivity and 100% specificity, showing significantly higher uptake in affected versus normal lung (P<0.0001).
Why the study?
What is the sensitivity and specificity of FDG PET/CT in diagnosing pulmonary lymphangitic carcinomatosis?
Population
35 patients with pulmonary lymphangitic carcinomatosis confirmed at follow-up chest CT or histopathologic…
Comparison
FDG PET/CT imaging vs Follow-up chest CT or histopathologic examination
Design
Cohort, Two radiologists independently assessed abnormal PET activity in the…
Authors
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May support FDG PET/CT for suspected cases; leaves open prospective validation before practice change.
Observational (n=35)
What is the sensitivity and specificity of FDG PET/CT in diagnosing pulmonary lymphangitic carcinomatosis?
Absolute Event Rate: 1.37% vs 0.51%
p-value: p=<0.0001
FDG PET/CT demonstrates high specificity (100%) and good sensitivity (86%) for detecting pulmonary lymphangitic carcinomatosis, though focal disease may be missed.
Prakash et al. (2009) conducted an observational in Pulmonary lymphangitic carcinomatosis (n=35). FDG PET/CT vs. Normal lung was evaluated on Mean standardized uptake value (SUV) (p=<0.0001). FDG PET/CT detected pulmonary lymphangitic carcinomatosis with 86% sensitivity and 100% specificity, showing significantly higher uptake in affected versus normal lung (P<0.0001).
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