Key result
Genetic heterogeneity is evident in primary endocardial fibroelastosis, with familial cases suggesting X-linked recessive, autosomal dominant, and autosomal recessive inheritance patterns.
Population
26 cases of primary endocardial fibroelastosis collected over a ten-year period
Design
Case_series
Authors
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May inform genetic counseling in familial endocardial fibroelastosis; leaves open inheritance patterns pending larger studies.
Observational (n=26)
Yes
Primary endocardial fibroelastosis exhibits genetic heterogeneity with multiple possible inheritance patterns, highlighting the importance of accurate family history despite most cases being sporadic.
Westwood et al. (1975) conducted an observational in Primary endocardial fibroelastosis (n=26). Genetic inheritance was evaluated on Inheritance patterns. Genetic heterogeneity is evident in primary endocardial fibroelastosis, with familial cases suggesting X-linked recessive, autosomal dominant, and autosomal recessive inheritance patterns.
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