Answers are grounded in this paper and cite their sources.
Telomerase activity is detected in most types of human tumors, but it is almost undetectable in normal somatic cells; therefore, telomerase is a promising therapeutic target. The present review describes various approaches to telomerase inhibition, namely, antisense therapy, RNA interference, and the use of ribozymes and agents interacting with the telomeric G-quadruplex. The use of these compounds in clinical research is analyzed in the review.
No takes yet. Share an insight, caveat, or question.
Глухов et al. (2011) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: