Key result
Major aortic annulus diameters measured using a modified 2DTEE five-chamber view showed good correlation with MDCT diameter (r = 0.79, p < 0.001) and allowed accurate TAVR sizing in 75% of patients.
Why the study?
MDCT is the gold standard for aortic annulus sizing before TAVR but has limited applicability in subgroups like atrial fibrillation and chronic kidney disease, while 2DTEE has traditionally been limited to anteroposterior diameter measurement.
Does a modified 2DTEE approach accurately measure the major aortic annulus diameter compared to MDCT in patients undergoing TAVR?
Observational (n=76)
Blinded assessors
No
Does a modified 2DTEE approach accurately measure the major aortic annulus diameter compared to MDCT in patients undergoing TAVR?
Effect estimate: r = 0.79
p-value: p=<0.001
A novel 2DTEE modified five-chamber view provides major aortic annulus diameter measurements that correlate well with MDCT, offering a reliable alternative for TAVR sizing in patients with contraindications to MDCT.
Supports modified 2DTEE for TAVR annulus sizing when MDCT contraindicated; leaves open need for prospective outcome validation.
BACKGROUND: Multidetector computed tomography (MDCT) is the gold standard in annulus sizing before transcatheter aortic valve replacement (TAVR). However, MDCT has limited applicability in specific subgroups of patients, such as those with atrial fibrillation and chronic kidney disease. Two-dimensional transesophageal echocardiography (2DTEE) has traditionally been limited to the long-axis measurement of the anteroposterior diameter of the aortic annulus. We describe a new 2DTEE approach for the measurement of the major diameter of the aortic annulus. METHODS: Seventy-six patients with symptomatic severe aortic valve stenosis and high surgical risk underwent MDCT and 2DTEE before TAVR. A modified five-chamber view was used to measure the major aortic annulus diameter. This was obtained starting from a mid-esophageal four chamber and retracting the TEE probe up until the left ventricular outflow tract and the left and noncoronary aortic cusps were visualized: major aortic annulus diameter was measured as the distance between their insertion points in systole. RESULTS: < 0.0001). Using factsheet-derived sizing criteria, 2DTEE alone would have allowed accurate sizing in 75% of patients, with 21% of oversizing predominantly with smaller annuli. CONCLUSIONS: We describe a new method for 2DTEE measurement of the major aortic annulus diameter; this approach is simple, correlates with MDCT, and allows adequate TAVR sizing in most patients. These findings may help in the assessment of patients with contraindications to or inadequate MDCT images.
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Librera et al. (2021) conducted an observational in Symptomatic severe aortic valve stenosis (n=76). Two-dimensional transesophageal echocardiography (2DTEE) modified five-chamber view vs. Multidetector computed tomography (MDCT) was evaluated on Correlation between major aortic annulus diameter measured by 2DTEE and MDCT (r = 0.79, p=<0.001). Major aortic annulus diameters measured using a modified 2DTEE five-chamber view showed good correlation with MDCT diameter (r = 0.79, p < 0.001) and allowed accurate TAVR sizing in 75% of patients.
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