Dermatofibrosarcoma Protuberans of the Breast: A Rare Case Report

Figures

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  Fig. 1.. Low-to-medium power photomicrograph of the DFSP showing the characteristic feature of the tumor mass being separated from the overlying epidermis (top, outlined) by a thin, cell-poor free zone (Grenz zone). The dermal component shows a dense proliferation of spindled cells.

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  Fig. 2.. Low-power photomicrograph illustrating the storiform or cartwheel pattern of the neoplastic spindled cells within the deep dermal/subcutaneous tissue. The clear, acellular area (center) may represent an artifact, a myxoid change, or a section of a blood vessel.

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  Fig. 3.. Low-to-medium power photomicrograph similar to Figure 1, highlighting the superficial aspect of the tumor, its proximity to the epidermis (top, outlined), and the characteristic appearance of the spindled cell proliferation in the underlying dermis.

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  Fig. 4.. High-power photomicrograph demonstrating the whorled and intersecting short bundles of spindled cells and associated collagen, typical of the tumor’s architectural pattern. The contrast in the staining intensity may represent different areas of the tumor (e.g., more cellular vs. more collagenous/fibrous).

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  Fig. 5.. Medium-power photomicrograph showing the deep portion of the tumor invading the dermis/subcutaneous tissue and entrapping an adnexal structure, likely a hair follicle (center-left), a common feature of DFSP. The surrounding tumor cells exhibit the classic fascicular and storiform growth pattern.

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  Fig. 6.. Medium-power photomicrograph focusing on the dense, monotonous proliferation of spindled tumor cells forming the characteristic storiform pattern (cells radiating out from a central point, like spokes on a wheel). The pale vertical cleft may be an artifact of tissue processing or a vascular space.

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  Fig. 7.. Breast ultrasound (US) shows a distance measurement of 2.24 cm marked by calipers (Dist 2.24 cm), indicating the size of a structure or region of interest within the breast tissue. Also shows typical echogenicity of breast tissue, including the hypoechoic (darker) subcutaneous fat and the glandular/stromal layers. The primary purpose of these images is to visualize the internal structure of the breast, often to screen for or characterize masses, cysts, or other abnormalities.