Key result
Heart rate gradually increased from 73 to 78 beats per minute in the 90 minutes preceding a ventricular arrhythmia in patients with coronary artery disease and an implantable defibrillator.
Population
38 patients with ischemic heart disease and an implantable cardioverter defibrillator who experienced at…
Design
Cohort
Follow-up
90 minutes preceding arrhythmia
Authors
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A progressive increase in heart rate and global heart rate variability occurs up to 90 minutes before a ventricular arrhythmia in patients with ischemic heart disease and an ICD, suggesting an early build-up of sympathovagal imbalance.
Observational (n=38)
Yes
Absolute Event Rate: 78% vs 73%
p-value: p=<0.01
A progressive increase in heart rate and global heart rate variability occurs up to 90 minutes before a ventricular arrhythmia in patients with ischemic heart disease and an ICD, suggesting an early build-up of sympathovagal imbalance.
Copie et al. (2003) conducted an observational in Coronary artery disease with ventricular arrhythmias (n=38). Time preceding ventricular arrhythmia vs. Baseline (90 minutes prior to arrhythmia) was evaluated on Heart rate in the 90 minutes preceding ventricular arrhythmia (p=<0.01). Heart rate gradually increased from 73 to 78 beats per minute in the 90 minutes preceding a ventricular arrhythmia in patients with coronary artery disease and an implantable defibrillator.
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