Key result
Intraduodenal acarbose (100 mg) markedly attenuated the falls in systolic (P<0.01) and diastolic (P<0.05) blood pressure induced by intraduodenal sucrose in healthy older adults.
Why the study?
Does intraduodenal acarbose attenuate the hypotensive response and rise in splanchnic blood flow induced by intraduodenal sucrose in healthy older adults?
Does intraduodenal acarbose attenuate the hypotensive response and rise in splanchnic blood flow induced by intraduodenal sucrose in healthy older adults?
p-value: p=<0.01
Acarbose attenuates postprandial hypotension and splanchnic blood flow increases in older adults by slowing carbohydrate absorption, independent of gastric emptying.
No takes yet. Share an insight, caveat, or question.
Hypothesis-generating for acarbose in postprandial hypotension; prospective oral-dosing trials needed before any practice change.
Gentilcore et al. (2011) studied Healthy (n=8). Acarbose vs. Without acarbose was evaluated on Falls in systolic and diastolic blood pressure (p=<0.01). Intraduodenal acarbose (100 mg) markedly attenuated the falls in systolic (P<0.01) and diastolic (P<0.05) blood pressure induced by intraduodenal sucrose in healthy older adults.
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