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October 10, 2017Virology JournalOpen Access

Detection and phylogenetic analyses of spike genes in porcine epidemic diarrhea virus strains circulating in China in 2016–2017

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Key result

Porcine epidemic diarrhea virus was detected in 52.6% of diarrhea samples from pig farms in China, with phylogenetic analysis indicating the circulating strains belong to the virulent G2 group.

Population

116 diarrhea samples collected from pig farms in 6 Chinese provinces in 2016–2017

Design

Other

Authors

QZQiaoling ZhangJilin UniversityXLXinsheng LiuLanzhou Institute of Chemical PhysicsYFYuzhen FangLiaocheng University

Discussion

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Overview

Novel PEDV strains characterized in Chinese outbreaks; leaves open needs for updated surveillance and vaccines.

Study Design

Type

Cross-Sectional (n=116)

Multicenter

Yes

Structured PICO

P
Population
116 diarrhea samples collected from pig farms in 6 Chinese provinces in 2016-2017 to assess the prevalence and genetic diversity of porcine epidemic diarrhea virus.
E
Exposure
PCR detection for main porcine enteric pathogens and sequencing of complete S genes from 11 representative PEDV strains
O
Outcome
Detection rate of PEDV and genetic characteristics/phylogenetic analysis of the spike (S) gene

Epidemic strains of PEDV circulating in China in 2016-2017 are mainly virulent G2 group strains that genetically differ from the vaccine strain.

Cite This Study

Zhang et al. (2017) conducted a cross-sectional in Porcine epidemic diarrhea (n=116). Porcine epidemic diarrhea virus (PEDV) infection was evaluated on PEDV positivity rate. Porcine epidemic diarrhea virus was detected in 52.6% of diarrhea samples from pig farms in China, with phylogenetic analysis indicating the circulating strains belong to the virulent G2 group.

synapsesocial.com/papers/6a97a6e41545ec94a776e6dfhttps://doi.org/10.1186/s12985-017-0860-z
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